New-onset aortic dilatation in the population: a quarter-century follow-up.

ABSTRACT:

Background

Aortic size tends to increase with aging but the extent of this dynamic process has not been evaluated in long-term longitudinal population-based studies. We investigated the incidence of new-onset aortic root (AR) dilatation and its principal correlates among middle-aged adults over a 25-year time period.

Methods

A total of 471 participants with measurable echocardiographic parameters at baseline and after a 25-year follow-up were included in the analysis. Sex-specific upper limits of normality for absolute AR diameter, AR diameter indexed to body surface area (BSA) and to height were derived from healthy normotensive PAMELA participants.

Results

New AR dilatation occurred in 7.4% (AR/BSA), 9.1% (AR/height) and 14.6% (absolute AR), respectively. According

SUBMITTER: Cuspidi C 

PROVIDER: S-EPMC10584747 | biostudies-literature | 2023 Nov

REPOSITORIES: biostudies-literature