Clinical courses of acute kidney injury in hospitalized patients: a multistate analysis.

ABSTRACT: Persistence of acute kidney injury (AKI) or insufficient recovery of renal function was associated with reduced long-term survival and life quality. We quantified AKI trajectories and describe transitions through progression and recovery among hospitalized patients. 245,663 encounters from 128,271 patients admitted to UF Health between 2012 and 2019 were retrospectively categorized according to the worst AKI stage experienced within 24-h periods. Multistate models were fit for describing characteristics influencing transitions towards progressed or regressed AKI, discharge, and death. Effects of age, sex, race, admission comorbidities, and prolonged intensive care unit stay (ICU) on transition rates were examined via Cox proportional hazards models. About 20% of encounters had AKI; where 6

SUBMITTER: Adiyeke E 

PROVIDER: S-EPMC10584933 | biostudies-literature | 2023 Oct

REPOSITORIES: biostudies-literature