Meta-analysis of the association between toll-like receptor gene polymorphisms and hepatitis C virus infection.

ABSTRACT:

Objective

The objective of this study is to investigate the association between toll-like receptor (TLR) 3/7 gene polymorphisms and the infection by hepatitis C virus (HCV).

Methods

PubMed, Embase, Web of Science, Scopus, CNKI, Wanfang Data, and SinoMed were searched to identify studies focusing on the association between the TLR3 rs3775290 or the TLR7 rs179008 single nucleotide polymorphisms (SNPs) and the HCV infection. All the related articles were collected from the inception of each database to 15 January 2023. Our meta-analysis was conducted using the allelic model, the dominant model, and the recessive model. Outcomes were presented by odds ratio (ORs) and 95% confidence interval (95%CI). The heterogeneity across studies was assessed by the I² test. A subgr

SUBMITTER: Du Y 

PROVIDER: S-EPMC10585147 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature