Uncontrolled eating and sensation-seeking partially explain the prediction of future binge drinking from adolescent brain structure.

ABSTRACT: Binge drinking behavior in early adulthood can be predicted from brain structure during early adolescence with an accuracy of above 70%. We investigated whether this accurate prospective prediction of alcohol misuse behavior can be explained by psychometric variables such as personality traits or mental health comorbidities in a data-driven approach. We analyzed a subset of adolescents who did not have any prior binge drinking experience at age 14 (IMAGEN dataset, n = 555, 52.61% female). Participants underwent structural magnetic resonance imaging at age 14, binge drinking assessments at ages 14 and 22, and psychometric questionnaire assessments at ages 14 and 22. We derived structural brain features from T1-weighted magnetic resonance and diffusion tensor imaging. Using Machine Learning

SUBMITTER: Rane RP 

PROVIDER: S-EPMC10585345 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature