An Energy-Reduced Mediterranean Diet, Physical Activity, and Body Composition: An Interim Subgroup Analysis of the PREDIMED-Plus Randomized Clinical Trial.

ABSTRACT:

Importance

Strategies targeting body composition may help prevent chronic diseases in persons with excess weight, but randomized clinical trials evaluating lifestyle interventions have rarely reported effects on directly quantified body composition.

Objective

To evaluate the effects of a lifestyle weight-loss intervention on changes in overall and regional body composition.

Design, setting, and participants

The ongoing Prevención con Dieta Mediterránea-Plus (PREDIMED-Plus) randomized clinical trial is designed to test the effect of the intervention on cardiovascular disease prevention after 8 years of follow-up. The trial is being conducted in 23 Spanish research centers and includes men and women (age 55-75 years) with body mass index between 27 and 40 and metabolic

SUBMITTER: Konieczna J 

PROVIDER: S-EPMC10585413 | biostudies-literature | 2023 Oct

REPOSITORIES: biostudies-literature