Retinal and Choroidal Thickness in an Indigenous Population from Ghana: Comparison with Individuals with European or African Ancestry.

ABSTRACT:

Purpose

To evaluate the thickness of the macular retina and central choroid in an indigenous population from Ghana, Africa and to compare them with those measured among individuals with European or African ancestry.

Design

Cross-sectional study, systematic review, and meta-analyses.

Participants

Forty-two healthy Ghanaians, 37 healthy individuals with European ancestry, and an additional 1427 healthy subjects with African ancestry from previously published studies.

Methods

Macular retinal thickness in the fovea, parafovea, and perifovea and central choroidal thickness were extracted from OCT volume scans. Associations with ethnicity, age, and sex were assessed using mixed-effect regression models. Monte Carlo simulations were performed to determine the sensitiv

SUBMITTER: Zouache MA 

PROVIDER: S-EPMC10585639 | biostudies-literature | 2024 Mar-Apr

REPOSITORIES: biostudies-literature