Association between NDRG1 protein expression and aggressive features of breast cancer: a systematic review and meta-analysis.

ABSTRACT:

Background

N-myc downstream-regulated gene-1 (NDRG1) is well-described as a potent metastasis suppressor, but its role in human breast cancer remains controversial and unclear. Therefore, the present study utilized a systematic review and meta-analysis approach to synthesize the association between NDRG1 protein expression and the aggressive characteristics of breast cancer.

Methods

The protocol for the systematic review and meta-analysis was registered on the PROSPERO website (CRD42023414814). Relevant articles were searched for in PubMed, Scopus, Embase, MEDLINE, and Ovid between March 30, 2023, and May 5, 2023. The included studies were critically evaluated using the Joanna Briggs Institute critical appraisal tools. The results from individual studies were qualitatively s

SUBMITTER: Kotepui K 

PROVIDER: S-EPMC10585795 | biostudies-literature | 2023 Oct

REPOSITORIES: biostudies-literature