Differential effects of plant-based flours on metabolic homeostasis and the gut microbiota in high-fat fed rats.

ABSTRACT:

Background

The gut microbiome is a salient contributor to the development of obesity, and diet is the greatest modifier of the gut microbiome, which highlights the need to better understand how specific diets alter the gut microbiota to impact metabolic disease. Increased dietary fiber intake shifts the gut microbiome and improves energy and glucose homeostasis. Dietary fibers are found in various plant-based flours which vary in fiber composition. However, the comparative efficacy of specific plant-based flours to improve energy homeostasis and the mechanism by which this occurs is not well characterized.

Methods

In experiment 1, obese rats were fed a high fat diet (HFD) supplemented with four different plant-based flours for 12 weeks. Barley flour (BF), oat bran (OB), whea

SUBMITTER: Martinez TM 

PROVIDER: S-EPMC10585811 | biostudies-literature | 2023 Oct

REPOSITORIES: biostudies-literature