Perfluoroalkyl substances in umbilical cord blood and blood pressure in offspring: a prospective cohort study.

ABSTRACT:

Background

Humans are widely exposed to perfluoroalkyl substances (PFAS), which have been found to be associated with various adverse birth outcomes. As blood pressure (BP) is an important parameter reflecting cardiovascular health in early life, it is necessary to investigate the association of PFAS exposure during early lifetime and BP in childhood. Therefore, we investigated the potential association between PFAS levels in umbilical cord blood and BP of the offspring at 4 years of age in a prospective cohort study.

Methods

PFAS in umbilical cord blood samples after birth were measured with high-performance liquid chromatography/tandem mass spectrometry in the Shanghai Birth Cohort. BP was measured at 4 years of age in the offspring. Multiple linear regression model was us

SUBMITTER: Xu Z 

PROVIDER: S-EPMC10585876 | biostudies-literature | 2023 Oct

REPOSITORIES: biostudies-literature