The Clinical Profile of Tremor in Parkinson's Disease.

ABSTRACT:

Background

Tremor is one of the most troublesome manifestations of Parkinson's Disease (PD) and its response to dopaminergic medication is variable; an evidence-based framework of PD tremor is lacking yet needed to inform future investigations.

Objective

To perform a comprehensive longitudinal analysis on the clinical characteristics, course and response to dopaminergic medication of tremor in de-novo PD.

Methods

Three hundred ninety-seven participants were recruited in the Parkinson Progressive Markers Initiative, a prospective observational cohort study in early de-novo PD. Rest, postural and kinetic tremor scores were extracted from the Movement Disorders Society-Unified Parkinson's Disease Rating Scale. Progression from baseline to 7-year follow-up of rest, postur

SUBMITTER: Pasquini J 

PROVIDER: S-EPMC10585977 | biostudies-literature | 2023 Oct

REPOSITORIES: biostudies-literature