A high-throughput structural system biology approach to increase structure representation of proteins from Clostridioides difficile.
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ABSTRACT:
SUBMITTER: Rosas-Lemus M
PROVIDER: S-EPMC10586155 | biostudies-literature | 2023 Oct
REPOSITORIES: biostudies-literature
Publications
A high-throughput structural system biology approach to increase structure representation of proteins from <i>Clostridioides difficile</i>.
Rosas-Lemus Monica M Dey Supratim S Minasov George G Tan Kemin K Anderson Spencer M SM Brunzelle Joseph J Nocadello Salvatore S Shabalin Ivan I Filippova Ekaterina E Halavaty Andrei A Kim Youngchang Y Maltseva Natalia N Osipiuk Jerzy J Minor Wladek W Joachimiak Andrzej A Savchenko Alexei A Anderson Wayne F WF Satchell Karla J F KJF
Microbiology resource announcements 20230925 10
<i>Clostridioides difficile</i> causes life-threatening gastrointestinal infections. It is a high-risk pathogen due to a lack of effective treatments, antimicrobial resistance, and a poorly conserved genomic core. Herein, we report 30 X-ray structures from a structure genomics pipeline spanning 13 years, representing 10.2% of the X-ray structures for this important pathogen. ...[more]
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