A high-throughput structural system biology approach to increase structure representation of proteins from Clostridioides difficile.

ABSTRACT: Clostridioides difficile causes life-threatening gastrointestinal infections. It is a high-risk pathogen due to a lack of effective treatments, antimicrobial resistance, and a poorly conserved genomic core. Herein, we report 30 X-ray structures from a structure genomics pipeline spanning 13 years, representing 10.2% of the X-ray structures for this important pathogen.

SUBMITTER: Rosas-Lemus M 

PROVIDER: S-EPMC10586155 | biostudies-literature | 2023 Oct

REPOSITORIES: biostudies-literature