Unveiling the Three-Step Model for the Interaction of Imidazolium-Based Ionic Liquids on Albumin.

ABSTRACT: The effect of the ionic liquids (ILs) 1-methyl-3-tetradecylimidazolium chloride ([C₁₄MIM][Cl]), 1-dodecyl-3-methylimidazolium chloride ([C₁₂MIM][Cl]), and 1-decyl-methylimidazolium chloride ([C₁₀MIM][Cl]) on the structure of bovine serum albumin (BSA) was investigated by fluorescence spectroscopy, ultraviolet-visible (UV-vis) spectroscopy, small-angle X-ray scattering (SAXS), and molecular dynamics (MD) simulations. Concerning the fluorescence measurements, we observed a blue shift and a fluorescence quenching as the IL concentration increased in the solution. Such behavior was observed for all three studied imidazolium-based ILs, being larger as the number of methylene groups in the alkyl chain increased. UV-vis absorbance measurements indicate that even a

SUBMITTER: Raw J 

PROVIDER: S-EPMC10586182 | biostudies-literature | 2023 Oct

REPOSITORIES: biostudies-literature