Fabry disease and sleep disorders: a systematic review.

ABSTRACT:

Background

Fabry disease (FD) is an X-chromosome-linked disorder characterized by a reduced or complete absence of the enzyme α-galactosidase, resulting in the accumulation of lysosomal globotriaosylceramide. Despite the presence of these deposits in multiple organs, the problem of sleep disorders within this population has very rarely been documented.

Objective

This study aimed to investigate the types and prevalence of sleep disorders among patients with FD.

Methods

Screening of the following medical databases using key terms was performed on 10 February 2023: PubMed, Scopus, and Embase. A total of 136 records were identified. The quality assessment of the studies was conducted by using tools from the National Institutes of Health (NIH) and critical appraisal tools

SUBMITTER: Blaszczyk B 

PROVIDER: S-EPMC10586315 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature