Dosimetric response of Gafchromic^™ EBT-XD film to therapeutic protons.

ABSTRACT: EBT-XD model of Gafchromic^™ films has a broader optimal dynamic dose range, up to 40 Gy, compared to its predecessor models. This characteristic has made EBT-XD films suitable for high-dose applications such as stereotactic body radiotherapy and stereotactic radiosurgery, as well as ultra-high dose rate FLASH radiotherapy. The purpose of the current study was to characterize the dependence of EBT-XD film response on linear energy transfer (LET) and dose rate of therapeutic protons from a synchrotron. A clinical spot-scanning proton beam was used to study LET dependence at three dose-averaged LET (LET_d) values of 1.0 keV/µm, 3.6 keV/µm, and 7.6 keV/µm. A research proton beamline was used to study dose rate dependence at 150 Gy/second in the FLASH mode and 0.3 Gy/second

SUBMITTER: Guan F 

PROVIDER: S-EPMC10586355 | biostudies-literature | 2023 Mar

REPOSITORIES: biostudies-literature