Predictive value of serum β2-microglobulin in cardiac valve calcification in maintenance hemodialysis patients.

ABSTRACT:

Background

Cardiac valve calcification (CVC) is associated with adverse cardiovascular events. We studied the risk factors of CVC in maintenance hemodialysis (MHD) patients and the value of serum β2-microglobulin (β2-MG) levels in predicting the incidence of CVC. β2-MG is a middle molecular weight toxin. In recent years, researchers found that elevated blood β2-MG was associated with coronary, thoracic, and abdominal aortic calcifications with significant correlations. β2-MG has been emerging as a strong biomarker for cardiovascular mortality in uremic patients but its role in CVC is not well studied. This study looked specifically at CVC occurrence in relation to β2-MG for MHD patients.

Methods

Patients who underwent MHD for more than 3 months in the First People's Hospital

SUBMITTER: Shen Y 

PROVIDER: S-EPMC10586954 | biostudies-literature | 2023 Sep

REPOSITORIES: biostudies-literature