Comparison of early and late ⁶⁸Ga-FAPI-46-PET in 33 patients with possible recurrence of pancreatic ductal adenocarcinomas.

ABSTRACT: Positron emission tomography with ⁶⁸Gallium (⁶⁸Ga) labeled inhibitors of fibroblast activation protein (⁶⁸Ga-FAPI-PET) is a promising imaging technique for patients with recurrent pancreatic ductal adenocarcinomas (PDAC). To date, it is not clear if different acquisition timepoints for ⁶⁸Ga-FAPI-PET may result in comparable imaging information and if repetitive ⁶⁸Ga-FAPI-PET imaging may add diagnostic value to single timepoint acquisition for recurrent PDAC. Here we analyzed retrospectively early (20 min p.i.) and late (60 min p.i.) ⁶⁸Ga-FAPI-PET imaging using FAPI-46 of 33 patients with possible recurrence of PDAC concerning detection rates and uptake over time of local recurrences, metastases, inflammatory lesions of the p

SUBMITTER: Hoppner J 

PROVIDER: S-EPMC10587145 | biostudies-literature | 2023 Oct

REPOSITORIES: biostudies-literature