Inherited myogenic abilities in muscle precursor cells defined by the mitochondrial complex I-encoding protein.

ABSTRACT: Skeletal muscle comprises different muscle fibers, including slow- and fast-type muscles, and satellite cells (SCs), which exist in individual muscle fibers and possess different myogenic properties. Previously, we reported that myoblasts (MBs) from slow-type enriched soleus (SOL) had a high potential to self-renew compared with cells derived from fast-type enriched tibialis anterior (TA). However, whether the functionality of myogenic cells in adult muscles is attributed to the muscle fiber in which they reside and whether the characteristics of myogenic cells derived from slow- and fast-type fibers can be distinguished at the genetic level remain unknown. Global gene expression analysis revealed that the myogenic potential of MBs was independent of the muscle fiber type they reside in bu

SUBMITTER: Motohashi N 

PROVIDER: S-EPMC10587152 | biostudies-literature | 2023 Oct

REPOSITORIES: biostudies-literature