Tuning aminopolycarboxylate chelators for efficient complexation of trivalent actinides.

ABSTRACT: The complexation of trivalent lanthanides and minor actinides (Am³⁺, Cm³⁺, and Cf³⁺) by the acyclic aminopolycarboxylate chelators 6,6'-((ethane-1,2-diylbis-((carboxymethyl)azanediyl))bis-(methylene))dipicolinic acid (H₄octapa) and 6,6'-((((4-(1-(2-(2-(2-hydroxyethoxy)ethoxy)ethyl)-1H-1,2,3-triazol-4-yl)pyridine-2,6-diyl)bis-(methylene))bis-((carboxymethyl)azanediyl))bis-(methylene)) dipicolinic acid (H₄pypa-peg) were studied using potentiometry, spectroscopy, competitive complexation liquid-liquid extraction, and ab initio molecular dynamics simulations. Two studied reagents are strong multidentate chelators, well-suited for applications seeking radiometal coordination for in-vivo delivery and f-element isolation. The previously repor

SUBMITTER: Pilgrim CD 

PROVIDER: S-EPMC10587169 | biostudies-literature | 2023 Oct

REPOSITORIES: biostudies-literature