Health-related quality of life of children with first onset steroid-sensitive nephrotic syndrome.

ABSTRACT: This study assessed HRQoL and emotional and behavioral difficulties (EBD) and associated variables in children with first onset SSNS. While relapsing steroid-sensitive nephrotic syndrome (SSNS) in children is associated with lower health-related quality of life (HRQoL), little is known about first onset. Four weeks after onset, children (2-16 years) and/or their parents who participated in a randomized placebo-controlled trial, completed the Pediatric Quality of Life Inventory 4.0 (PedsQL) and Strengths and Difficulties Questionnaire (SDQ) to measure HRQoL and EBD, respectively. Total and subscale scores and the proportion of children with impaired HRQoL (> 1 SD below the mean of the reference group) or SDQ clinical scores (< 10^th and > 90^th percentile) were compared

SUBMITTER: Veltkamp F 

PROVIDER: S-EPMC10587200 | biostudies-literature | 2023 Oct

REPOSITORIES: biostudies-literature