Estimating the effect of active detection and isolation on Clostridioides difficile infections in a bone marrow transplant unit.

ABSTRACT:

Objective

To model the effects of active detection and isolation (ADI) regarding Clostridioides difficile infection (CDI) in the bone marrow transplant (BMT) unit of our hospital.

Setting

ADI was implemented in a 21-patient bone marrow unit.

Patients

Patients were bone marrow recipients on this unit.

Interventions

We compared active ADI, in which patients who tested positive for colonization of C. difficile before their hospital stay were placed under extra contact precautions, with cases not under ADI.

Results

Within the BMT unit, ADI reduced total cases of CDI by 24.5% per year and reduced hospital-acquired cases by ∼84%. The results from our simulations also suggest that ADI can save ∼$67,600 per year in healthcare costs.

Conclusions<

SUBMITTER: Reagan KA 

PROVIDER: S-EPMC10587385 | biostudies-literature | 2023 Oct

REPOSITORIES: biostudies-literature