Associations between Chronic Kidney Disease and Thinning of Neuroretinal Layers in Multiethnic Asian and White Populations.

ABSTRACT:

Purpose

To evaluate the relationships between chronic kidney disease (CKD) with retinal nerve fiber layer (RNFL) and ganglion cell-inner plexiform layer (GCIPL) thickness profiles of eyes in Asian and White populations.

Design

Cross-sectional analysis.

Participants

A total of 5066 Asian participants (1367 Malays, 1772 Indians, and 1927 Chinese) from the Singapore Epidemiology of Eye Diseases Study (SEED) were included, consisting of 9594 eyes for peripapillary RNFL analysis and 8661 eyes for GCIPL analysis. Additionally, 45 064 White participants (87 649 eyes) from the United Kingdom Biobank (UKBB) were included for both macular RNFL analysis and GCIPL analysis.

Methods

Nonglaucoma participants aged ≥ 40 years with complete data for estimated glomerular filtrat

SUBMITTER: Majithia S 

PROVIDER: S-EPMC10587624 | biostudies-literature | 2024 Jan-Feb

REPOSITORIES: biostudies-literature