Evaluation of Foveal Cone and Muller Cells in Epiretinal Membrane using Adaptive Optics OCT.

ABSTRACT:

Objective

To investigate cellular-level morphological alterations in the retinal neuroglia in eyes with epiretinal membrane (ERM).

Design

Prospective cross-sectional, observational study (November 2020-May 2022).

Subjects and controls

We included 41 eyes with unilateral idiopathic ERM and 33 healthy eyes of healthy volunteers.

Methods

We examined the foveal microstructures in all eyes using adaptive optics OCT (AO-OCT) with axial and lateral resolutions of 3.4 and 3.0 μm, respectively. Adaptive optics OCT images were acquired for a 2.5° (728 μm) area at the foveal center.

Main outcome measures

Foveal microstructures on AO-OCT images, best-corrected visual acuity (BCVA) in logarithm of the minimum angle of resolution units, and associations between these

SUBMITTER: Ishikura M 

PROVIDER: S-EPMC10587629 | biostudies-literature | 2024 Jan-Feb

REPOSITORIES: biostudies-literature