Neighborhood poverty during childhood prospectively predicts adolescent functional brain network architecture.

ABSTRACT: Family poverty has been associated with altered brain structure, function, and connectivity in youth. However, few studies have examined how disadvantage within the broader neighborhood may influence functional brain network organization. The present study leveraged a longitudinal community sample of 538 twins living in low-income neighborhoods to evaluate the prospective association between exposure to neighborhood poverty during childhood (6-10 y) with functional network architecture during adolescence (8-19 y). Using resting-state and task-based fMRI, we generated two latent measures that captured intrinsic brain organization across the whole-brain and network levels - network segregation and network segregation-integration balance. While age was positively associated with network segre

SUBMITTER: Michael C 

PROVIDER: S-EPMC10587714 | biostudies-literature | 2023 Dec

REPOSITORIES: biostudies-literature