Dental Extractions Before Radiation Therapy and the Risk of Osteoradionecrosis in Patients With Head and Neck Cancer.

ABSTRACT:

Importance

Patients with head and neck cancer undergo extraction of teeth with poor prognoses to minimize post-radiation therapy (RT) extractions, which are known to cause osteoradionecrosis (ORN). However, many patients are required to start RT before the extraction sites are completely healed. The role of pre-RT extractions in the development of ORN has been disputed in literature.

Objective

To determine whether the timing of pre-RT dental extractions is associated with ORN development in patients with head and neck cancer.

Design, setting, and participants

This retrospective cohort study was conducted at a single institution (Princess Margaret Cancer Centre, Toronto, Canada) between January 1, 2011, and January 1, 2018, and included 879 patients with head and neck

SUBMITTER: Lee J 

PROVIDER: S-EPMC10587826 | biostudies-literature | 2023 Dec

REPOSITORIES: biostudies-literature