Clinical outcomes following different stenting techniques for coronary bifurcation lesions: a systematic review and network meta-analysis of randomised controlled trials.

ABSTRACT:

Background

Controversy still exists regarding the optimal treatment of coronary bifurcation lesions.

Aims

We aimed to analyse the evidence from randomised controlled trials (RCTs) to compare outcomes following different bifurcation stenting techniques.

Methods

We systematically searched for RCTs comparing different techniques published up to July 2022. We then conducted a pairwise meta-analysis to compare outcomes between provisional stenting (PS) versus upfront 2-stent techniques. Moreover, we performed a network meta-analysis (NMA) to compare all strategies with each other. The primary endpoint was major adverse cardiac events (MACE).

Results

Twenty-four RCTs (6,890 patients) analysed PS, T-stenting, double-kissing (DK)-crush, crush, or culotte stenting. The

SUBMITTER: Bujak K 

PROVIDER: S-EPMC10587845 | biostudies-literature | 2023 Oct

REPOSITORIES: biostudies-literature