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Highly sensitive and selective detection of triphosgene with a 2-(2'-hydroxyphenyl)benzimidazole derived fluorescent probe.


ABSTRACT: In this work, a 2-(2'-hydroxyphenyl)benzimidazole derived fluorescent probe, 2-(2'-hydroxy-4'-aminophenyl)benzimidazole (4-AHBI), was synthesized and its fluorescent behavior toward triphosgene were evaluated. The results showed that 4-AHBI exhibited high sensitivity (limit of detection, 0.08 nM) and excellent selectivity for triphosgene over other acyl chlorides including phosgene in CH2Cl2 solution. Moreover, 4-AHBI loaded test strips were prepared for the practical sensing of triphosgene.

SUBMITTER: Bi WZ 

PROVIDER: S-EPMC10587890 | biostudies-literature | 2023 Oct

REPOSITORIES: biostudies-literature

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Highly sensitive and selective detection of triphosgene with a 2-(2'-hydroxyphenyl)benzimidazole derived fluorescent probe.

Bi Wen-Zhu WZ   Geng Yang Y   Zhang Wen-Jie WJ   Li Chen-Yu CY   Ni Chu-Sen CS   Ma Qiu-Juan QJ   Feng Su-Xiang SX   Chen Xiao-Lan XL   Qu Ling-Bo LB  

RSC advances 20231020 44


In this work, a 2-(2'-hydroxyphenyl)benzimidazole derived fluorescent probe, 2-(2'-hydroxy-4'-aminophenyl)benzimidazole (4-AHBI), was synthesized and its fluorescent behavior toward triphosgene were evaluated. The results showed that 4-AHBI exhibited high sensitivity (limit of detection, 0.08 nM) and excellent selectivity for triphosgene over other acyl chlorides including phosgene in CH<sub>2</sub>Cl<sub>2</sub> solution. Moreover, 4-AHBI loaded test strips were prepared for the practical sensi  ...[more]

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