Associations between depression and cancer risk among patients with diabetes mellitus: A population-based cohort study.

ABSTRACT:

Background

The co-occurrence of depression and diabetes mellitus has been linked to an increased risk of developing cancer. This study aimed to investigate whether depression further amplifies the risk of cancer among individuals with diabetes.

Methods

This population-based matched cohort study utilized Taiwan's National Health Insurance claims database. A total of 85,489 newly diagnosed diabetic patients with depressive disorders were selected, along with 427,445 comparison subjects. The matching process involved age, sex, and the calendar year of diabetes onset. The average follow-up duration for the two cohorts was 6.4 and 6.5 years, respectively. The primary outcome of interest was the occurrence of overall cancer or cancer at specific anatomical sites.

Results

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SUBMITTER: Shi-Heng W 

PROVIDER: S-EPMC10587979 | biostudies-literature | 2023 Oct

REPOSITORIES: biostudies-literature