Circulating chemerin levels in preeclampsia: a systematic review and meta-analysis.

ABSTRACT:

Background

Preeclampsia (PE) is a new-onset pregnancy-specific disorder with a high prevalence that leads to over 70 000 maternal and 500 000 foetal fatalities worldwide each year. The level of chemerin, a newly identified adipokine, is increased in diabetic and obese patients. Currently, there are several studies describing the relationship between maternal circulating chemerin levels and PE. Therefore, this study aimed to assess their association in pooled samples.

Methods

Four databases were systematically searched to identify potential studies that reported circulating chemerin levels in PE and normal pregnancy groups. Standardized mean differences (SMDs), 95% confidence intervals (CIs), and 95% prediction intervals (PIs) were calculated using a random-effects meta-analy

SUBMITTER: Yin Y 

PROVIDER: S-EPMC10588206 | biostudies-literature | 2023 Oct

REPOSITORIES: biostudies-literature