Lower versus higher oxygen targets for out-of-hospital cardiac arrest: a systematic review and meta-analysis.

ABSTRACT:

Background

Supplemental oxygen is commonly administered to patients after out-of-hospital cardiac arrest. However, the findings from studies on oxygen targeting for out-of-hospital cardiac arrest are inconclusive. Thus, we conducted a systematic review and meta-analysis to evaluate the impact of lower oxygen target compared with higher oxygen target on patients after out-of-hospital cardiac arrest.

Methods

We searched the Cochrane Central Register of Controlled Trials, MEDLINE, Embase, from inception to February 6, 2023, for randomized controlled trials comparing lower and higher oxygen target in adults (aged ≥ 18 years) after out-of-hospital cardiac arrest. We screened studies and extracted data independently. The primary outcome was mortality at 90 days after cardiac arres

SUBMITTER: Cheng X 

PROVIDER: S-EPMC10588244 | biostudies-literature | 2023 Oct

REPOSITORIES: biostudies-literature