Using immunovascular characteristics to predict very early recurrence and prognosis of resectable intrahepatic cholangiocarcinoma.

ABSTRACT:

Objective

To predict the very early recurrence (VER) of patients with intrahepatic cholangiocarcinoma (ICC) based on TLSs and MVI status, and further perform prognosis stratifications.

Methods

A total of 160, 51 ICC patients from two institutions between May 2012 and July 2022 were retrospectively included as training, external validation cohort. Clinical, radiological and pathological variables were evaluated and collected. Univariate and multivariate analysis were applied to select the significant factors related to VER of ICC. The factors selected were combined to perform stratification of overall survival (OS) using the Kaplan-Meier method with the log-rank test.

Results

Overall, 39 patients (24.4%) had VER, whereas 121 (75.6%) did not (non-VER group). In the trai

SUBMITTER: Xu Y 

PROVIDER: S-EPMC10588260 | biostudies-literature | 2023 Oct

REPOSITORIES: biostudies-literature