Calcified plaque harboring lipidic materials associates with no-reflow phenomenon after PCI in stable CAD.

ABSTRACT: Calcified atheroma has been viewed conventionally as stable lesion which less likely increases no-reflow phenomenon. Given that lipidic materials triggers the formation of calcification, lipidic materials could exist within calcified lesion, which may cause no-reflow phenomenon after PCI. The REASSURE-NIRS registry (NCT04864171) employed near-infrared spectroscopy and intravascular ultrasound imaging to evaluate maximum 4-mm lipid-core burden index (maxLCBI_4mm) at target lesions containing small (maximum calcification arc < 180°: n = 272) and large calcification (maximum calcification arc ≥ 180°: n = 189) in stable CAD patients. The associations of maxLCBI_4mm with corrected TIMI frame count (CTFC) and no-reflow phenomenon after PCI were analyzed in patients with targe

SUBMITTER: Hosoda H 

PROVIDER: S-EPMC10589149 | biostudies-literature | 2023 Oct

REPOSITORIES: biostudies-literature