Adult Medical Cannabinoid Use and Changes in Prescription Controlled Substance Use.

ABSTRACT: Introduction: Nonopioid-based strategies for managing chronic noncancer pain are needed to help reduce overdose deaths. Although lab studies and population-level data suggest that cannabinoids could provide opioid-sparing effects, among medical cannabis participants they may also impact overdose risk by modifying other controlled substance use such as sedative hypnotics. However, no study has combined observational data at the individual level to empirically address interactions between the use of cannabinoids and prescribed controlled substances. Methods: Electronic health records, including prescription drug monitoring program data, from a large multisite medical cannabis program in New York State were abstracted for all participants with noncancer pain and recently prescri

SUBMITTER: Williams AR 

PROVIDER: S-EPMC10589493 | biostudies-literature | 2023 Oct

REPOSITORIES: biostudies-literature