Adolescent and caregiver preferences for juvenile idiopathic arthritis treatment: a discrete-choice experiment.

ABSTRACT:

Background

This study aimed to elicit and quantify preferences for treatments for juvenile idiopathic arthritis (JIA).

Methods

We conducted a discrete-choice experiment among adolescents with JIA in the United States (US) (n = 197) and United Kingdom (UK) (n = 100) and caregivers of children with JIA in the US (n = 207) and UK (n = 200). In a series of questions, respondents chose between experimentally designed profiles for hypothetical JIA treatments that varied in efficacy (symptom control; time until next flare-up), side effects (stomachache, nausea, and vomiting; headaches), mode and frequency of administration, and the need for combination therapy. Using a random-parameters logit model, we estimated preference weights for these attributes, from which we derived their c

SUBMITTER: McErlane F 

PROVIDER: S-EPMC10589988 | biostudies-literature | 2023 Oct

REPOSITORIES: biostudies-literature