A comprehensive analysis of gut and skin microbiota in canine atopic dermatitis in Shiba Inu dogs.

ABSTRACT:

Background

Like its human counterpart, canine atopic dermatitis (cAD) is a chronic relapsing condition; thus, most cAD-affected dogs will require lifelong treatment to maintain an acceptable quality of life. A potential intervention is modulation of the composition of gut microbiota, and in fact, probiotic treatment has been proposed and tried in human atopic dermatitis (AD) patients. Since dogs are currently receiving intensive medical care, this will be the same option for dogs, while evidence of gut dysbiosis in cAD is still missing, although skin microbial profiling in cAD has been conducted in several studies. Therefore, we conducted a comprehensive analysis of both gut and skin microbiota in cAD in one specific cAD-predisposed breed, Shiba Inu. Additionally, we evaluated the

SUBMITTER: Thomsen M 

PROVIDER: S-EPMC10590023 | biostudies-literature | 2023 Oct

REPOSITORIES: biostudies-literature