The prognostic value of the tertiary lymphoid structure in gastrointestinal cancers.

ABSTRACT:

Background

Numerous studies and research papers have provided evidence suggesting that tertiary lymphoid structures (TLS) play a crucial role in combating and suppressing tumor growth and progression. Despite the wealth of information on the significance of TLS in various types of cancer, their prognostic value in gastrointestinal (GI) cancers remains uncertain. Therefore, this meta-analysis investigated the prognostic value of TLS in GI cancers.

Methods

We searched Web of science, Pubmed, Embase and Cochrane Library for studies that met the requirements as of May 1, 2023, and the hazard ratio (HR) and the corresponding 95% confidence interval (CI) were included in the analysis. The bioinformatics analysis results based on the TCGA database are used to supplement our researc

SUBMITTER: Yu A 

PROVIDER: S-EPMC10590053 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature