Atrial pacing minimization in sinus node dysfunction and risk of incident atrial fibrillation: a randomized trial.

ABSTRACT:

Background and aims

High percentages of atrial pacing have been associated with an increased risk of atrial fibrillation. This study is aimed at evaluating whether atrial pacing minimization in patients with sinus node dysfunction reduces the incidence of atrial fibrillation.

Methods

In a nationwide, randomized controlled trial, 540 patients with sinus node dysfunction and an indication for first pacemaker implantation were assigned to pacing programmed to a base rate of 60 bpm and rate-adaptive pacing (DDDR-60) or pacing programmed to a base rate of 40 bpm without rate-adaptive pacing (DDD-40). Patients were followed on remote monitoring for 2 years. The primary endpoint was time to first episode of atrial fibrillation longer than 6 min. Secondary endpoints included longer

SUBMITTER: Kronborg MB 

PROVIDER: S-EPMC10590128 | biostudies-literature | 2023 Oct

REPOSITORIES: biostudies-literature