Metastasis pattern and prognosis of large cell neuroendocrine carcinoma: a population-based study.

ABSTRACT:

Purpose

As a rare type of tumor, the metastasis pattern of large cell neuroendocrine carcinoma (LCNEC) is still unclear. Our aim was to investigate metastatic patterns and develop a predictive model of prognosis in patients with advanced LCNEC.

Methods

Patients of LCNEC diagnosed between 2010-2015 from the Surveillance, Epidemiology and End Results (SEER) database were retrospectively included. Chi-square test was used for baseline characteristics analysis. Survival differences were assessed using Kaplan-Meier curves. Independent prognostic factors identified by multivariate Cox proportional risk model were used for the construction of nomogram.

Results

557 eligible patients with metastasis LCNEC (median (IQR), 64 (56 to 72) years; 323 males) were included in this res

SUBMITTER: Jiang T 

PROVIDER: S-EPMC10590330 | biostudies-literature | 2023 Nov

REPOSITORIES: biostudies-literature