Non-invasive detection of early microvascular changes in juveniles with type 1 diabetes.

ABSTRACT:

Aims/hypothesis

The study aimed to assess the usefulness of capillaroscopy and photoplethysmography in the search for early vascular anomalies in children with type 1 diabetes.

Methods

One hundred sixty children and adolescents aged 6-18, 125 patients with type 1 diabetes, and 35 healthy volunteers were enrolled in the study. We performed a detailed clinical evaluation, anthropometric measurements, nailfold capillaroscopy, and photoplethysmography.

Results

Patients with diabetes had more often abnormal morphology in capillaroscopy (68.60%, p = 0.019), enlarged capillaries (32.6%, p = 0.006), and more often more over five meandering capillaries (20.90%, p = 0.026) compared to healthy controls. Meandering capillaries correlated with higher parameters of nutritional stat

SUBMITTER: Bogusz-Gorna K 

PROVIDER: S-EPMC10590527 | biostudies-literature | 2023 Oct

REPOSITORIES: biostudies-literature