Immune-Related Genes in the Pathogenesis of Atherosclerosis: Based on Sex Differences.

ABSTRACT:

Purpose

Atherosclerosis is still a global public problem with increasing incidence rate and mortality. It has been found that gender factors play an important role in the progression of atherosclerosis. However, few people explore gender related atherosclerosis at the level of genes and immune cells. The purpose of this study was to determine genetic and immune cell differences between male and female samples.

Patients and methods

This study aims to identify differential genes between male and female samples in the GSE43292 dataset. The focus will be on identifying immune-related genes (IRGs) among these differentially expressed genes. Subsequently, Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) analysis will be employed to explore the enrichment of IR

SUBMITTER: Zhang P 

PROVIDER: S-EPMC10590557 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature