Diversity and independent evolutionary profiling of rodent-borne viruses in Hainan, a tropical island of China.

ABSTRACT: The risk of emerging infectious diseases (EID) is increasing globally. More than 60% of EIDs worldwide are caused by animal-borne pathogens. This study aimed to characterize the virome, analyze the phylogenetic evolution, and determine the diversity of rodent-borne viruses in Hainan Province, China. We collected 682 anal and throat samples from rodents, combined them into 28 pools according to their species and location, and processed them for next-generation sequencing and bioinformatics analysis. The diverse viral contigs closely related to mammals were assigned to 22 viral families. Molecular clues of the important rodent-borne viruses were further identified by polymerase chain reaction for phylogenetic analysis and annotation of genetic characteristics such as arenavirus, coronavirus,

SUBMITTER: Li Y 

PROVIDER: S-EPMC10590688 | biostudies-literature | 2023 Oct

REPOSITORIES: biostudies-literature