Survival analysis over a 20-year period of a Brazilian cohort of blood donors coinfected HIV-HCV.

ABSTRACT: Among individuals coinfected with HCV and HIV, studies of mortality from non-hepatic causes have shown inconsistent results. The aim of this study was to investigate the contribution of HCV and HIV co-infection to mortality from hepatic and non-hepatic causes in Brazil. This retrospective cohort study included blood donors from Fundação Pró-Sangue de São Paulo (FPS) who were followed from 1994 to 2016 to compare mortality and its causes between HIV-HCV coinfected individuals versus those seronegative for all tested infections. Records from the FPS database and the Mortality Information System were linked through a probabilistic record Relationship (RL). The Hazard Ratio (HR) was estimated using Cox multiple regression models. HCV-HIV coinfected individuals compared to seronegative individu

SUBMITTER: de Menezes Filho HR 

PROVIDER: S-EPMC10590849 | biostudies-literature | 2023 Sep-Oct

REPOSITORIES: biostudies-literature