The Liquid Biopsy Consortium: Challenges and opportunities for early cancer detection and monitoring.

ABSTRACT: The emerging field of liquid biopsy stands at the forefront of novel diagnostic strategies for cancer and other diseases. Liquid biopsy allows minimally invasive molecular characterization of cancers for diagnosis, patient stratification to therapy, and longitudinal monitoring. Liquid biopsy strategies include detection and monitoring of circulating tumor cells, cell-free DNA, and extracellular vesicles. In this review, we address the current understanding and the role of existing liquid-biopsy-based modalities in cancer diagnostics and monitoring. We specifically focus on the technical and clinical challenges associated with liquid biopsy and biomarker development being addressed by the Liquid Biopsy Consortium, established through the National Cancer Institute. The Liquid Biopsy Consorti

SUBMITTER: Batool SM 

PROVIDER: S-EPMC10591039 | biostudies-literature | 2023 Oct

REPOSITORIES: biostudies-literature