Endocrine treatment near the end of life among older women with metastatic breast cancer: a nationwide cohort study.

ABSTRACT:

Background

The appropriate time to discontinue chemotherapy at the end of life has been widely discussed. In contrast, few studies have investigated the patterns of endocrine treatment near death. In this study, we aimed to investigate the end-of-life endocrine treatment patterns of older women with metastatic breast cancer and explore characteristics associated with treatment.

Methods

A retrospective cohort study of all older women (age ≥65 years) with hormone receptor-positive breast cancer who died in Sweden, 2016 - 2020. We used routinely collected administrative and health data with national coverage. Treatment initiation was defined as dispensing during the last three months of life with a nine-month washout period, while continuation and discontinuation were assessed

SUBMITTER: Szilcz M 

PROVIDER: S-EPMC10591323 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature