Association between metabolic syndrome and early-stage colorectal cancer.

ABSTRACT:

Background

Accumulating studies have suggested metabolic syndrome (MetS) contributed to colorectal cancer (CRC) development. However, advanced CRC might decrease the detection proportion of MetS due to chronic malnutrition, we included patients with early-stage CRC to examine the associations among MetS, onset age, and different tumorigenesis pathways of CRC.

Methods

We conducted a retrospective study that included 638 patients with early-stage CRC from January 2014 to December 2018. Patient information was collected from the medical record system and further refined during the follow-up. Stratified analyses of the associations between MetS and different stratification factors were determined by the Cochran‒Mantel‒Haenszel test.

Results

There were 16 (13.3%) and 111 (

SUBMITTER: Zhang C 

PROVIDER: S-EPMC10591414 | biostudies-literature | 2023 Oct

REPOSITORIES: biostudies-literature