Relationships between age, fMRI correlates of familiarity and familiarity-based memory performance under single and dual task conditions.

ABSTRACT: Using fMRI, we investigated the effects of age and divided attention on the neural correlates of familiarity and their relationship with memory performance. At study, word pairs were visually presented to young and older participants under the requirement to make a relational judgment on each pair. Participants were then scanned while undertaking an associative recognition test under single and dual (auditory tone detection) task conditions. The test items comprised studied, rearranged (words from different studied pairs) and new word pairs. fMRI familiarity effects were operationalized as greater activity elicited by studied pairs incorrectly identified as 'rearranged' than by correctly rejected new pairs. The reverse contrast was employed to identify 'novelty' effects. Behavioral familia

SUBMITTER: de Chastelaine M 

PROVIDER: S-EPMC10591814 | biostudies-literature | 2023 Oct

REPOSITORIES: biostudies-literature