Left ventricular ejection fraction and long-term outcomes in women presenting with signs and symptoms of ischaemia.

ABSTRACT:

Background

Although women are known to have a relatively higher left ventricular ejection fraction (LVEF) compared with men, a sex-neutral LVEF threshold continues to be used for clinical management. We sought to investigate the relationship among high (>65%), normal (55%-65%) and low (<55%) LVEF and long-term all-cause mortality and major adverse cardiovascular events (MACEs) in women presenting with suspected myocardial ischaemia.

Methods

A total of 734 women from the Women's Ischemia Syndrome Evaluation (WISE) were analysed. LVEF was calculated by invasive left ventriculography. The relationship between baseline characteristics, LVEF and outcomes was evaluated. A multivariable Cox regression model was used to assess the association of LVEF with outcomes, after adjusting f

SUBMITTER: Wu S 

PROVIDER: S-EPMC10592103 | biostudies-literature | 2023 Oct

REPOSITORIES: biostudies-literature