Impact of Tumor Size and Management on Survival in Small Gastric Gastrointestinal Stromal Tumors.

ABSTRACT:

Background

Society guidelines remain inconsistent on the role of endoscopic and radiographic surveillance as an alternative to surgical resection of small gastric gastrointestinal stromal tumors (GISTs). Herein, we aimed to assess survival among patients with gastric GISTs undergoing observation versus surgical resection, stratified by tumor size.

Methods

The National Cancer Database (NCDB) was queried for gastric GISTs < 2 cm diagnosed from 2010-2017. Patients were stratified by management strategy-observation vs surgical resection. The primary outcome, overall survival (OS), was examined with Kaplan-Meier and multivariable Cox proportional hazard methods. Subgroup analyses were conducted on tumors < 1 cm and 1-2 cm in size.

Results

Altogether, 1208 patients were ide

SUBMITTER: Rhodin KE 

PROVIDER: S-EPMC10592390 | biostudies-literature | 2023 Oct

REPOSITORIES: biostudies-literature