Epilepsy and sleep characteristics are associated with diminished 24-h memory retention in older adults with epilepsy.

ABSTRACT:

Objective

Individuals with epilepsy often have memory difficulties, and older adults with epilepsy are especially vulnerable, due to the additive effect of aging. The goal of this study was to assess factors that are associated with 24-h memory retention in older adults with epilepsy.

Methods

Fifty-five adults with epilepsy, all aged >50 years, performed a declarative memory task involving the recall of the positions of 15 card pairs on a computer screen prior to a 24-h ambulatory electroencephalogram (EEG). We assessed the percentage of encoded card pairs that were correctly recalled after 24 h (24-h retention rate). EEGs were evaluated for the presence and frequency of scalp interictal epileptiform activity (IEA) and scored for total sleep. Global slow wave activity (SWA)

SUBMITTER: Sarkis RA 

PROVIDER: S-EPMC10592425 | biostudies-literature | 2023 Oct

REPOSITORIES: biostudies-literature