<i>Wolbachia</i> enhances the survival of <i>Drosophila</i> infected with fungal pathogens.

ABSTRACT: Wolbachia bacteria of arthropods are at the forefront of basic and translational research on multipartite host-symbiont-pathogen interactions. These microbes are vertically inherited from mother to offspring via the cytoplasm. They are the most widespread endosymbionts on the planet due to their infamous ability to manipulate the reproduction of their hosts to spread themselves in a population, and to provide a variety of fitness benefits to their hosts. Importantly, some strains of Wolbachia can inhibit viral pathogenesis within and between arthropod hosts. Mosquitoes carrying the wMel Wolbachia strain of Drosophila melanogaster have a greatly reduced capacity to spread viruses like dengue and Zika to humans. Therefore, Wolbachia are the basis of

SUBMITTER: Perlmutter JI 

PROVIDER: S-EPMC10592616 | biostudies-literature | 2023 Oct

REPOSITORIES: biostudies-literature