Network state dynamics underpin craving in a transdiagnostic population.

ABSTRACT: Emerging fMRI brain dynamic methods present a unique opportunity to capture how brain region interactions across time give rise to evolving affective and motivational states. As the unfolding experience and regulation of affective states affect psychopathology and well-being, it is important to elucidate their underlying time-varying brain responses. Here, we developed a novel framework to identify network states specific to an affective state of interest and examine how their instantaneous engagement contributed to its experience. This framework investigated network state dynamics underlying craving, a clinically meaningful and changeable state. In a transdiagnostic sample of healthy controls and individuals diagnosed with or at risk for craving-related disorders (N=252), we utilized conn

SUBMITTER: Ye J 

PROVIDER: S-EPMC10593000 | biostudies-literature | 2023 Oct

REPOSITORIES: biostudies-literature